Mimic (1997)

In this classic sci-fi tale of unforseen consequences, etymologist Mira Sorvino develops a genetically-engineered insect intended to kill disease-carrying cockroaches and then die off. Instead, a new breed of lethal, giant bugs emerges in the New York City sewer systems. Lots of creepy CGI insects everywhere you look. Not for the phobic or easily-disgusted.

The cast includes: Mira Sorvino, Jeremy Northam, Giancarlo Giannini, Charles S. Dutton,  Josh Brolin, and F. Murray Abraham.

Directed by Guillermo del Toro.